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. 2019 Dec;6(4):587-597.
doi: 10.1007/s40744-019-00179-2. Epub 2019 Oct 28.

Physical and Emotional Burden of Rheumatoid Arthritis: Data from RA Matters, a Web-Based Survey of Patients and Healthcare Professionals

Rieke Alten  1 , Mart van de Laar  2 , Francesco De Leonardis  3 , Nicole Tietz  3 , Mariana Guerreiro  3 , Ronald van Vollenhoven  4
Affiliations

Physical and Emotional Burden of Rheumatoid Arthritis: Data from RA Matters, a Web-Based Survey of Patients and Healthcare Professionals

Rieke Alten et al. Rheumatol Ther. 2019 Dec.

Abstract

Introduction: This survey assessed the impact of rheumatoid arthritis (RA) on the lives of patients based on the perceptions of both patients and healthcare professionals (HCPs).

Methods: This is a cross-sectional survey of patients with RA. Data were collected from patients and HCPs who manage RA using a structured, closed-ended questionnaire in their local language. Respondents for the survey were recruited from survey panels of verified unique responses. The survey focused on the impact of disease on four domains: daily activities, relationships, work and aspirations.

Results: Overall, 1231 adult patients with RA and 270 rheumatologists or other HCPs were surveyed between November 2016 and February 2017. Almost one in three patients believed that the impact of RA is not well understood by people without the disease. Fifty-eight percent [95% confidence interval (CI) 55-61%] of patients felt frustrated when they were unable to undertake or complete daily activities because of their disease. Fifty-seven percent (95% CI 54-60%) of patients wished to be able to accept their life with RA. Forty-three percent (95% CI 40-46%) of patients hoped that the physical impact of RA will be better understood in future. Forty percent (95% CI 37-43%) of patients were forced to take long-term leave/retirement or experienced slow career progression since being diagnosed with RA. Twenty-three percent (95% CI 21-25%) of patients had difficulties in taking care of personal grooming, whereas 8% (95% CI 6-10%) of patients reported that RA ruined their life. Similar responses were observed among HCPs.

Conclusion: Patients and HCPs feel that the physical and emotional impact of RA is not well understood by people without the disease. In RA treatment decisions, patients' personal goals and patient-reported outcomes should be taken into consideration along with clinical targets.

Funding: Eli Lilly and Company (Indianapolis, IN, USA).

Keywords: Burden of illness; HCPs; Patient goals; Patients; Quality of life; Questionnaire; RA Matters; Rheumatoid arthritis; Survey.

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Conflict of interest statement

Rieke Alten has received research grants and consultancy fees from Eli Lilly and Company, Pfizer and Galapagos. Mart van de Laar has received research grants from Eli Lilly and Company, Pfizer, Merck, AbbVie and Janssen Cilag, and consulting fees from Sanofi Genzyme, Eli Lilly and Company, Pfizer, Merck, AbbVie and Janssen Cilag. Francesco De Leonardis is an employee and shareholder of Eli Lilly and Company. Nicole Tietz is an employee and shareholder of Eli Lilly and Company. Mariana Guerreiro is an employee and shareholder of Eli Lilly and Company. Ronald van Vollenhoven has received research grants from BMS, GSK, Eli Lilly and Company, Pfizer and UCB, and consultancy honoraria from AbbVie, AstraZeneca, Biogen, Biotest, Celgene, GSK, Janssen, Eli Lilly and Company, Pfizer, Servier and UCB.

Figures

Fig. 1
Fig. 1
Survey flow
See this image and copyright information in PMC

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