Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Jul 29;6(8):ofz349.
doi: 10.1093/ofid/ofz349. eCollection 2019 Aug.

Eight-Year-Old Male With Primary Amebic Meningoencephalitis

Affiliations

Eight-Year-Old Male With Primary Amebic Meningoencephalitis

Chairut Vareechon et al. Open Forum Infect Dis. .

Abstract

Naegleria fowleri is a thermophilic free-living amoeba that is found in warm, fresh water and causes primary amebic meningoencephalitis (PAM). The following report demonstrates the rapid and destructive clinical features of PAM in an 8-year-old male who presented with severe headaches approximately 12 days after swimming in a hot spring.

Keywords: Naegleria fowleri; PAM; primary amebic meningoencephalitis.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Giemsa stain of the cerebrospinal fluid.

References

    1. Vargas-Zepeda J, Gómez-Alcalá AV, Vásquez-Morales JA, et al. . Successful treatment of Naegleria fowleri meningoencephalitis by using intravenous amphotericin B, fluconazole and rifampicin. Arch Med Res 2005; 36:83–6. - PubMed
    1. Linam WM, Ahmed M, Cope JR, et al. . Successful treatment of an adolescent with Naegleria fowleri primary amebic meningoencephalitis. Pediatrics 2015; 135:e744–8. - PMC - PubMed
    1. Colon BL, Rice CA, Guy RK, Kyle DE. Phenotypic screens reveal posaconazole as a rapidly acting amebicidal combination partner for treatment of primary amoebic meningoencephalitis. J Infect Dis 2019; 219:1095–103. - PMC - PubMed
    1. Cope JR, Conrad DA, Cohen N, et al. . Use of the novel therapeutic agent miltefosine for the treatment of primary amebic meningoencephalitis: report of 1 fatal and 1 surviving case. Clin Infect Dis 2016; 62:774–6. - PMC - PubMed
    1. Yoder JS, Eddy BA, Visvesvara GS, et al. . The epidemiology of primary amoebic meningoencephalitis in the USA, 1962-2008. Epidemiol Infect 2010; 138:968–75. - PubMed