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Review
. 2019 May 9;13(6):526-532.
doi: 10.1177/1559827619845335. eCollection 2019 Nov-Dec.

Psychosocial Determinants of Chronic Disease: Implications for Lifestyle Medicine

Garry Egger  1   2   3 , John Stevens  1   2   3 , Andrew Binns  1   2   3 , Bob Morgan  1   2   3
Affiliations
Review

Psychosocial Determinants of Chronic Disease: Implications for Lifestyle Medicine

Garry Egger et al. Am J Lifestyle Med. .

Abstract

We have previously identified a number of "determinants" of chronic disease, using the acronym NASTIE ODOURS. These have been given the collective term "anthropogens," in this journal and other publications, to help direct the management of modern chronic ailments to a monocausal focus, akin to that afforded infectious diseases by the "germ theory." We suggested the acronym NASTIE ODOURS as a starting point for a taxonomy of lifestyle medicine determinants. In the current article, we add 3, less quantifiable, but currently increasingly more important psychosocial experiences to these: Lack of Meaning, Alienation, and Loss of culture, changing the previous acronym to NASTIE MAL ODOURS. As with other determinants, all have accumulating evidence of an underlying low-grade, systemic, inflammatory physiological base ("metaflammation"), but with the need for further research to solidify these findings.

Keywords: alienation; chronic disease; determinants; loss of culture; meaning; psychosocial.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
A hierarchy of lifestyle/environmental determinants in chronic disease “causality.”
Figure 2.
Figure 2.
An iceberg analogy of the interactions between lifestyle/environmental determinants
See this image and copyright information in PMC

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References

    1. American College of Lifestyle Medicine. https://lifestylemedicine.org Accessed November 30, 2017.
    1. Rippe JM. Lifestyle Medicine. 2nd ed. London, England: CRC Press; 2013.
    1. Mechanick JI, Kushner RF. Lifestyle Medicine: A Manual for Clinical Practice. New York, NY: Springer; 2016.
    1. Egger G, Binns A, Rossner S, Sagner M. Lifestyle Medicine: Lifestyle, the Environment and Preventive Medicine in Health and Disease. 3rd ed. London, England: Academic Press; 2017.
    1. Sagner M, Katz D, Egger G, et al. Lifestyle medicine potential for reversing a world of chronic disease epidemics: from cell to community. Int J Clin Pract. 2014;68:1289-1292. - PubMed

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