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Multicenter Study
. 2020 Feb;27(2):47-55.
doi: 10.1002/jhbp.695. Epub 2019 Dec 11.

A multicenter prospective registration study on laparoscopic pancreatectomy in Japan: report on the assessment of 1,429 patients

Takao Ohtsuka  1 , Yuichi Nagakawa  2 , Hirochika Toyama  3 , Yutaka Takeda  4 , Atsuyuki Maeda  5 , Yusuke Kumamoto  6 , Yoshiharu Nakamura  7 , Kazuki Hashida  8 , Goro Honda  9 , Kengo Fukuzawa  10 , Eiji Toyoda  11 , Minoru Tanabe  12 , Naoto Gotohda  13 , Ippei Matsumoto  14 , Tomoki Ryu  15 , Ichiro Uyama  16 , Toru Kojima  17 , Michiaki Unno  18 , Daisuke Ichikawa  19 , Yosuke Inoue  20 , Hiroyoshi Matsukawa  21 , Takeshi Sudo  22 , Kyoichi Takaori  23 , Hiroki Yamaue  24 , Susumu Eguchi  25 , Munenori Tahara  26 , Makoto Shinzeki  27 , Hidetoshi Eguchi  28 , Masanao Kurata  29 , Mamoru Morimoto  30 , Hiromitsu Hayashi  31 , Shigeru Marubashi  32 , Masafumi Inomata  33 , Kenjiro Kimura  34 , Koji Amaya  35 , Masayuki Sho  36 , Ryuichi Yoshida  37 , Akihiro Murata  38 , Hideyuki Yoshitomi  39 , Kenichi Hakamada  40 , Masafumi Yasunaga  41 , Nobutsugu Abe  42 , Masayoshi Hioki  43 , Masaru Tsuchiya  44 , Takeyuki Misawa  45 , Yasuji Seyama  46 , Hirokazu Noshiro  47 , Eiji Sakamoto  48 , Kiyoshi Hasegawa  49 , Yasunari Kawabata  50 , Yoichiro Uchida  51 , Shinichiro Kameyama  52 , Saiho Ko  53 , Takashi Takao  54 , Kenji Kitahara  55 , Shin Nakahira  56 , Hideo Baba  57 , Masahiko Watanabe  58   59 , Masakazu Yamamoto  60   61 , Masafumi Nakamura  1   62
Affiliations
Multicenter Study

A multicenter prospective registration study on laparoscopic pancreatectomy in Japan: report on the assessment of 1,429 patients

Takao Ohtsuka et al. J Hepatobiliary Pancreat Sci. 2020 Feb.

Abstract

Background: Prospective studies are needed to understand the safety and feasibility of laparoscopic pancreatectomy. The aim of the present study was to describe laparoscopic pancreatectomy currently undertaken in Japan, using a prospective registration system.

Methods: Patient characteristics and planned operations were registered preoperatively, and then the performed operation and outcomes were reported using an online system. Collected data were also compared between institutions based on their level of experience. This study was registered with UMIN000022836.

Results: Available data were obtained from 1,429 patients at 100 Japanese institutions, including 1,197 laparoscopic distal pancreatectomies (LDPs) and 232 laparoscopic pancreatoduodenectomies (LPDs). The rates of completion for planned operations were 92% for LDP and 91% for LPD. Postoperative complication rates after LDP and LPD were 17% and 30%, and 90-day mortality rates were 0.3% and 0.4%, respectively. Shorter operation time, less blood loss, and lower incidence of pancreatic fistula were observed in institutions experienced in LDP. A higher rate of pure laparoscopic procedure and shorter operation time were noted in institutions experienced with LPD.

Conclusion: LDPs and LPDs are performed safely in Japan, especially in experienced institutions. Our data could support the next challenges in the field of laparoscopic pancreatectomy.

Keywords: Distal pancreatectomy; Laparoscopic pancreatectomy; Pancreatoduodenectomy; Prospective registration.

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References

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