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Review
. 2019 Dec;33(4):907-932.
doi: 10.1016/j.idc.2019.07.003.

Novel Avian Influenza A Virus Infections of Humans

Affiliations
Review

Novel Avian Influenza A Virus Infections of Humans

Timothy M Uyeki et al. Infect Dis Clin North Am. 2019 Dec.

Abstract

A high index of suspicion and early diagnosis of avian influenza A virus infection is essential reduce transmission risk. Clinical suspicion relies on eliciting a history of recent exposure to poultry or to sick persons. Diagnosis requires collection of appropriate respiratory specimens. Patients with suspected infection should be isolated immediately and patients with lower respiratory tract disease should be placed on airborne precautions if possible. Antiviral treatment should be started as soon as possible based upon clinical suspicion while awaiting specific viral diagnosis. Corticosteroids and salicylates should be avoided. Clinical management focuses on supportive care of complications.

Keywords: Avian influenza; H5N1; H5N6; H7N9.

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References

    1. Chan PK. Outbreak of avian influenza A(H5N1) virus infection in Hong Kong in 1997. Clin Infect Dis 2002;34(Suppl 2):S58–64. - PubMed
    1. Peiris JS, Yu WC, Leung CW, et al. Re-emergence of fatal human influenza A subtype H5N1 disease. Lancet 2004;363(9409):617–9. - PMC - PubMed
    1. Webster RG, Peiris M, Chen H, et al. H5N1 outbreaks and enzootic influenza. Emerg Infect Dis 2006;12(1):3–8. - PMC - PubMed
    1. Lai S, Qin Y, Cowling BJ, et al. Global epidemiology of avian influenza A H5N1 virus infection in humans, 1997–2015: a systematic review of individual case data. Lancet Infect Dis 2016;16(7):e108–18. - PMC - PubMed
    1. Organization WH. Cumulative number of confirmed human cases of avian influenza A(H5N1) reported to WHO. 12 February 2019. 2019. Available at: https://www.who.int/influenza/human_animal_interface/2019_02_12_tableH5N.... Accessed April 12, 2019.

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