Characterization of Retinal Lesions Secondary to Hemophagocytic Lymphohistiocytosis With OCTA

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a high-mortality primary immunologic or genetic disorder that rarely presents with ocular symptoms. This is a case report of a 30-year-old Asian female with quiescent HLH in whom retinal lesions were identified during the third trimester of pregnancy. Multimodal imaging, including the first use of optical coherence tomography angiography (OCTA) in HLH, was used to characterize these lesions. OCTA was useful for distinguishing chronic ocular HLH from other uveitic syndromes affecting the retina. [Ophthalmic Surg Lasers Imaging Retina. 2019;50:653-655.].