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. 2020 May;159(5):e307-e309.
doi: 10.1016/j.jtcvs.2019.09.080. Epub 2019 Sep 30.

Increasing the United States heart transplant donor pool with donation after circulatory death

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Increasing the United States heart transplant donor pool with donation after circulatory death

Oliver K Jawitz et al. J Thorac Cardiovasc Surg. 2020 May.

Abstract

DCD heart donation has the potential to significantly increase the pool of available donor allografts in the US, by as much as 30%, and will lead to a substantial decrease in waiting list mortality.

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Figures

Figure 1.
Figure 1.
Application of the 2017 Messer DCD heart transplant donor selection criteria to the US DCD donor pool.
Figure 2.
Figure 2.
Predicted suitable DCD heart transplants (red) using 2017 Messer criteria and annual number of DBD heart transplants (gray). End-of-year waiting list volume (blue) provided by United Network for Organ Sharing (UNOS). Error bars indicate 95% confidence interval, estimated assuming binomial distribution and 65% DCD heart utilization rate from 2017 Messer study. DBD, donation after brain death; DCD, donation after circulatory death.

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References

    1. Messer S, et al., Outcome after heart transplantation from donation after circulatory-determined death donors. J Heart Lung Transplant, 2017. 36(12): p. 1311–1318. - PubMed
    1. Dhital KK, et al., Adult heart transplantation with distant procurement and ex-vivo preservation of donor hearts after circulatory death: a case series. Lancet, 2015. 385(9987): p. 2585–91. - PubMed
    1. Chew HC, et al., Outcomes of Donation After Circulatory Death Heart Transplantation in Australia. J Am Coll Cardiol, 2019. 73(12): p. 1447–1459. - PubMed
    1. White CW, et al., Transplantation of Hearts Donated after Circulatory Death. Front Cardiovasc Med, 2018. 5: p. 8. - PMC - PubMed
    1. Messer S, et al., The Potential of Transplanting Hearts From Donation After Circulatory Determined Death (DCD) Donors Within the United Kingdom. Journal of Heart and Lung Transplantation, 2015. 34(4): p. S275–S275.

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