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. 2019 Oct;18(11):826.

doi: 10.1038/d41573-019-00161-1.

Avoiding target misidentification

Stacey-Lynn Paiva

PMID: 31673126
DOI: 10.1038/d41573-019-00161-1

Comment

Avoiding target misidentification

Stacey-Lynn Paiva. Nat Rev Drug Discov. 2019 Oct.

. 2019 Oct;18(11):826.

doi: 10.1038/d41573-019-00161-1.

Author

Stacey-Lynn Paiva

PMID: 31673126
DOI: 10.1038/d41573-019-00161-1

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Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials.
Lin A, Giuliano CJ, Palladino A, John KM, Abramowicz C, Yuan ML, Sausville EL, Lukow DA, Liu L, Chait AR, Galluzzo ZC, Tucker C, Sheltzer JM. Lin A, et al. Sci Transl Med. 2019 Sep 11;11(509):eaaw8412. doi: 10.1126/scitranslmed.aaw8412. Sci Transl Med. 2019. PMID: 31511426 Free PMC article.

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Avoiding target misidentification

Avoiding target misidentification

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