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Editorial
. 2019 Oct;8(5):549-551.
doi: 10.21037/hbsn.2019.04.15.

Viewpoint: necroptosis influences the type of liver cancer via changes of hepatic microenvironment

Waqar K Saeed  1 , Dae Won Jun  1
Affiliations
Editorial

Viewpoint: necroptosis influences the type of liver cancer via changes of hepatic microenvironment

Waqar K Saeed et al. Hepatobiliary Surg Nutr. 2019 Oct.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Necroptosis changes hepatic microenvironment.
See this image and copyright information in PMC

Comment on

  • Necroptosis microenvironment directs lineage commitment in liver cancer.
    Seehawer M, Heinzmann F, D'Artista L, Harbig J, Roux PF, Hoenicke L, Dang H, Klotz S, Robinson L, Doré G, Rozenblum N, Kang TW, Chawla R, Buch T, Vucur M, Roth M, Zuber J, Luedde T, Sipos B, Longerich T, Heikenwälder M, Wang XW, Bischof O, Zender L. Seehawer M, et al. Nature. 2018 Oct;562(7725):69-75. doi: 10.1038/s41586-018-0519-y. Epub 2018 Sep 12. Nature. 2018. PMID: 30209397 Free PMC article.

References

    1. Saeed WK, Jun DW. Necroptosis: an emerging type of cell death in liver diseases. World J Gastroenterol 2014;20:12526-32. 10.3748/wjg.v20.i35.12526 - DOI - PMC - PubMed
    1. Seehawer M, Heinzmann F, D'Artista L, et al. Necroptosis microenvironment directs lineage commitment in liver cancer. Nature 2018;562:69-75. 10.1038/s41586-018-0519-y - DOI - PMC - PubMed
    1. Afonso MB, Rodrigues PM, Simao AL, et al. Activation of necroptosis in human and experimental cholestasis. Cell Death Dis 2016;7:e2390. 10.1038/cddis.2016.280 - DOI - PMC - PubMed
    1. Deng X, Zhang X, Li W, et al. Chronic Liver Injury Induces Conversion of Biliary Epithelial Cells into Hepatocytes. Cell Stem Cell 2018;23:114-22.e3. 10.1016/j.stem.2018.05.022 - DOI - PubMed
    1. Schaub JR, Huppert KA, Kurial SNT, et al. De novo formation of the biliary system by TGFbeta-mediated hepatocyte transdifferentiation. Nature 2018;557:247-51. 10.1038/s41586-018-0075-5 - DOI - PMC - PubMed