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Review
. 2020 Feb;61(1):93-103.
doi: 10.1007/s13353-019-00522-x. Epub 2019 Oct 31.

Nutrigenomics in livestock-recent advances

Affiliations
Review

Nutrigenomics in livestock-recent advances

Joanna Nowacka-Woszuk. J Appl Genet. 2020 Feb.

Abstract

The study of the effects of nutrients on genome functioning, in terms of gene transcription, protein levels, and epigenetic mechanisms, is referred to as nutrigenomics. Nutrigenomic studies in farm animals, as distinct from rodents, are limited by the high cost of keeping livestock, their long generational distance, and ethical aspects. Yet farm animals, and particularly pigs, can serve as valuable animal models for human gastrological diseases, since they possess similar size, physiology, and nutritional habits and can develop similar pathological states. In livestock, the effects of dietary modifications have mostly been studied with reference to effective breeding and their influence on production traits and animal health. The majority of such studies have looked at the impact of various sources and quantities of fat and protein, supplementation with microelements, and plant-derived additives. The period of life of the animal-whether prenatal, neonatal, or mature-is typically considered when a modified diet is used. This review presents a summary of recent nutrigenomic studies in livestock.

Keywords: DNA methylation; Diet; Epigenetics; Farm animals; Gene expression; Histone modifications.

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Conflict of interest statement

The author declares no conflicts of interest.

Figures

Fig. 1
Fig. 1
Overview of dietary aspects examined in nutrigenomic studies

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