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Review
. 2020 Feb;20(2):348-354.
doi: 10.1111/ajt.15680. Epub 2019 Nov 28.

Outstanding questions in transplantation: Tolerance

Joseph R Leventhal  1 , James M Mathew  1   2
Affiliations
Free article
Review

Outstanding questions in transplantation: Tolerance

Joseph R Leventhal et al. Am J Transplant. 2020 Feb.
Free article

Abstract

In 2017, the American Society of Transplantation (AST) launched the Outstanding Questions in Transplantation Research forum to stimulate a community-wide discussion of how the field is evolving and to help identify areas where a better dialogue between clinicians and researchers could result in great advancements. Tolerance emerged as a topic of great interest to the AST community. This minireview provides an overview of clinical transplantation tolerance. Historical background followed by a review of the current status of attempts to establish tolerance in the clinic, highlighting the dynamic online discussion surrounding this important topic from the AST Transplantation Research forum, is provided.

Keywords: immunosuppression/immune modulation; stem cells; tolerance: chimerism; tolerance: clinical; tolerance: mechanisms; translational research/science.

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References

REFERENCES

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