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Review
. 2019 Dec;66(6):1149-1161.
doi: 10.1016/j.pcl.2019.08.010.

Effects of Fetal Substance Exposure on Offspring Substance Use

Neil C Dodge  1 , Joseph L Jacobson  2 , Sandra W Jacobson  2
Affiliations
Review

Effects of Fetal Substance Exposure on Offspring Substance Use

Neil C Dodge et al. Pediatr Clin North Am. 2019 Dec.

Abstract

Prenatal exposure to alcohol and drugs is associated with physical, cognitive, and behavioral problems across the offspring's lifespan and an increased risk of alcohol and drug use in adolescent and young adult offspring. These prenatal effects continue to be evident after control for demographic background and parental alcohol and drug use. Behavior problems in childhood and adolescence associated with prenatal exposures may serve as a mediator of the prenatal exposure effects on offspring substance use.

Keywords: Adolescent alcohol; Adolescent substance use disorders; Cigarettes; Cocaine; Marijuana; Prenatal alcohol and drug exposure; Prenatal alcohol exposure; Substance abuse risk.

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