Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Oct;36(4):298-302.
doi: 10.1055/s-0039-1696649. Epub 2019 Oct 31.

Ablation of Intrahepatic Cholangiocarcinoma

Affiliations
Review

Ablation of Intrahepatic Cholangiocarcinoma

Jennifer Sweeney et al. Semin Intervent Radiol. 2019 Oct.

Abstract

Intrahepatic cholangiocarcinoma is the second most common primary liver cancer but represents only a small portion of all primary liver cancers. At the time of diagnosis, patients are often not surgical candidates due to tumor burden of other comorbidities. In addition, there is a very high rate of tumor recurrence after resection. Local regional therapies, specifically ablative therapies of radiofrequency ablation, microwave ablation, cryoablation, and irreversible electroporation, have proven to be beneficial with other hepatic tumors. The purpose of this review is to provide an overview and update of the medical literature demonstrating ablative therapy as a treatment option for intrahepatic cholangiocarcinoma.

Keywords: cryoablation; intrahepatic cholangiocarcinoma; microwave ablation; radiofrequency ablation.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest None declared.

References

    1. Razumilava N, Gores G J.Cholangiocarcinoma Lancet 2014383(9935):2168–2179. - PMC - PubMed
    1. Bridgewater J, Galle P R, Khan S A et al.Guidelines for the diagnosis and management of intrahepatic cholangiocarcinoma. J Hepatol. 2014;60(06):1268–1289. - PubMed
    1. DeOliveira M L, Cunningham S C, Cameron J L et al.Cholangiocarcinoma: thirty-one-year experience with 564 patients at a single institution. Ann Surg. 2007;245(05):755–762. - PMC - PubMed
    1. Nakanuma Y, Sato Y, Harada K, Sasaki M, Xu J, Ikeda H. Pathological classification of intrahepatic cholangiocarcinoma based on a new concept. World J Hepatol. 2010;2(12):419–427. - PMC - PubMed
    1. Park J, Kim M H, Kim K P et al.Natural history and prognostic factors of advanced cholangiocarcinoma without surgery, chemotherapy, or radiotherapy: a large-scale observational study. Gut Liver. 2009;3(04):298–305. - PMC - PubMed