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. 1988;22(4):353-5.
doi: 10.1007/BF00254245.

Disposition of ifosfamide in patients receiving ifosfamide infusion therapy for the treatment of cervical carcinoma

R Pearcey  1 , R Calvert, A Mehta
Affiliations

Disposition of ifosfamide in patients receiving ifosfamide infusion therapy for the treatment of cervical carcinoma

R Pearcey et al. Cancer Chemother Pharmacol. 1988.

Abstract

The disposition of ifosfamide was investigated in nine patients receiving a total of 23 72-h infusions. There was no linear relationship between steady-state plasma concentrations and either vomiting or CNS toxicity. The steady-state plasma concentrations were reproducible within patients, but there was a wide variation between patients. The progress of the disease did not affect the disposition of ifosfamide.

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