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. 2019 Sep 30;8(9):2753-2759.
doi: 10.4103/jfmpc.jfmpc_86_19. eCollection 2019 Sep.

Asthma exacerbation related to viral infections: An up to date summary

Mehdi Adeli  1   2   3 , Tamara El-Shareif  2 , Mohamed A Hendaus  1   2   3
Affiliations

Asthma exacerbation related to viral infections: An up to date summary

Mehdi Adeli et al. J Family Med Prim Care. .

Abstract

Asthma exacerbation can be a major life threatening event. Viruses have been pinned as the cause behind the vast majority of these exacerbations. The purpose of this short review is to explore the mechanisms behind these exacerbations, focusing mostly on viral infections as triggers. We will also be discussing the phenotypes prone to asthma exacerbation, the pathophysiology of viral induced asthma and ventilation patterns of asthmatic lungs. This manuscript will assist primary care physicians in delineating the proper pathophysiology of the disease as well as the management.

Keywords: Asthma; exacerbations; pulmonary function; virus-induced asthma.

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Conflict of interest statement

There are no conflicts of interest. Abbreviations: PEF, Peak Flow Meter; ILC2, Type 2 innate lymphoid cell; IFN-α, Interferon alpha; IFN-β, Interferon beta; INFλ, interferon Gama; EPA, Exacerbation Prone Asthma; FEV, Forced Expiratory Volume; IL5, Interleukin 5; IL25, Interleukin 25; IL32, Interleukin 32; RV16, Rhinovirus 16; GERD, Gastro-Esophageal Reflux Disease; BMI, Body Mass Index

Comment on

  • J Family Med Prim Care. 8(9):2751.

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