Making HIS mice more human-like

doi:10.1002/JLB.5CE1019-262R

Editorial

. 2020 Jan;107(1):9-10.

doi: 10.1002/JLB.5CE1019-262R. Epub 2019 Nov 4.

Making HIS mice more human-like

John A Simpson¹, Matthew E Brown¹

Affiliations

PMID: 31682279
DOI: 10.1002/JLB.5CE1019-262R

Editorial

Making HIS mice more human-like

John A Simpson et al. J Leukoc Biol. 2020 Jan.

. 2020 Jan;107(1):9-10.

doi: 10.1002/JLB.5CE1019-262R. Epub 2019 Nov 4.

Authors

John A Simpson¹, Matthew E Brown¹

Affiliation

¹ University of Wisconsin-Madison, Madison, WI, USA.

PMID: 31682279
DOI: 10.1002/JLB.5CE1019-262R

Abstract

Discussion on exhaustion/senescence marker profiles on human T cells in BRGSF-A2 humanized mice and how they resemble those in human samples; describes how this model fits into the humanized-mouse research field.

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Frontline Science: Exhaustion and senescence marker profiles on human T cells in BRGSF-A2 humanized mice resemble those in human samples.
Labarthe L, Henriquez S, Lambotte O, Di Santo JP, Le Grand R, Pflumio F, Arcangeli ML, Legrand N, Bourgeois C. Labarthe L, et al. J Leukoc Biol. 2020 Jan;107(1):27-42. doi: 10.1002/JLB.5HI1018-410RR. Epub 2019 Aug 4. J Leukoc Biol. 2020. PMID: 31378988

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References

REFERENCES

1. Shultz LD, Brehm MA, Garcia JV, Greiner DL. Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol. 2012;12(11):786-798.
1. Yao LC, Aryee KE, Cheng M, Kaur P, Keck JG, Brehm MA. Creation of PDX-bearing humanized mice to study immuno-oncology. Methods Mol Biol. 2019;1953:241-252.
1. Mold JE, Venkatasubrahmanyam SK, Burt TD, et al. Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. Science. 2010;330(6011):1695-1699.
1. Brown ME, Zhou Y, McIntosh BE,et al. A humanized mouse model generated using surplus neonatal tissue. Stem Cell Reports. 2018;10(4):1175-1183.
1. Makino S, Kunimoto K, Muraoka Y, Mizushima Y, Katagiri K, Tochino Y. Breeding of a non-obese, diabetic strain of mice. Jikken Dobutsu. 1980;29(1):1-13.

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[1] Shultz LD, Brehm MA, Garcia JV, Greiner DL. Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol. 2012;12(11):786-798.

[2] Shultz LD, Brehm MA, Garcia JV, Greiner DL. Humanized mice for immune system investigation: progress, promise and challenges. Nat Rev Immunol. 2012;12(11):786-798.

[3] Yao LC, Aryee KE, Cheng M, Kaur P, Keck JG, Brehm MA. Creation of PDX-bearing humanized mice to study immuno-oncology. Methods Mol Biol. 2019;1953:241-252.

[4] Yao LC, Aryee KE, Cheng M, Kaur P, Keck JG, Brehm MA. Creation of PDX-bearing humanized mice to study immuno-oncology. Methods Mol Biol. 2019;1953:241-252.

[5] Mold JE, Venkatasubrahmanyam SK, Burt TD, et al. Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. Science. 2010;330(6011):1695-1699.

[6] Mold JE, Venkatasubrahmanyam SK, Burt TD, et al. Fetal and adult hematopoietic stem cells give rise to distinct T cell lineages in humans. Science. 2010;330(6011):1695-1699.

[7] Brown ME, Zhou Y, McIntosh BE,et al. A humanized mouse model generated using surplus neonatal tissue. Stem Cell Reports. 2018;10(4):1175-1183.

[8] Brown ME, Zhou Y, McIntosh BE,et al. A humanized mouse model generated using surplus neonatal tissue. Stem Cell Reports. 2018;10(4):1175-1183.

[9] Makino S, Kunimoto K, Muraoka Y, Mizushima Y, Katagiri K, Tochino Y. Breeding of a non-obese, diabetic strain of mice. Jikken Dobutsu. 1980;29(1):1-13.

[10] Makino S, Kunimoto K, Muraoka Y, Mizushima Y, Katagiri K, Tochino Y. Breeding of a non-obese, diabetic strain of mice. Jikken Dobutsu. 1980;29(1):1-13.

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Making HIS mice more human-like

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Making HIS mice more human-like

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