Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Jun;72(3):373-6.

Macrophage and lymphocyte subpopulations in magnifying endoscopic lesions of Crohn's disease

P Gionchetti  1 , Y R Mahida, S Patel, D P Jewell
Affiliations

Macrophage and lymphocyte subpopulations in magnifying endoscopic lesions of Crohn's disease

P Gionchetti et al. Clin Exp Immunol. 1988 Jun.

Abstract

Using dye staining and a magnifying colonoscope, small lesions in the rectum of patients with Crohn's disease (which had otherwise appeared normal on sigmoidoscopy) can be detected. Subpopulations of macrophages and lymphocytes in the abnormal and adjacent normal areas of the rectum were studied using a panel of monoclonal antibodies. There was a distinct increase in RFD9+ and 3G8+ macrophages in the abnormal areas compared with the normal. The CD4:CD8 ratio of lymphocytes in the two areas remained unchanged.

PubMed Disclaimer

References

    1. J Clin Pathol. 1983 Apr;36(4):379-84 - PubMed
    1. Clin Exp Immunol. 1983 Sep;53(3):614-8 - PubMed
    1. Gut. 1984 Jan;25(1):32-40 - PubMed
    1. Clin Exp Immunol. 1984 Feb;55(2):377-87 - PubMed
    1. Gut. 1984 Apr;25(4):337-40 - PubMed

Publication types

Substances

LinkOut - more resources