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Review
. 2019 Nov 2;7(11):521.
doi: 10.3390/microorganisms7110521.

Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?

Cristian-Marian Popescu  1 , Aurora Livia Ursache  2 , Gavriela Feketea  3 , Corina Bocsan  4 , Laura Jimbu  5 , Oana Mesaros  6 , Michael Edwards  7 , Hongwei Wang  8 , Iulia Berceanu  9 , Alexandra Neaga  10 , Mihnea Zdrenghea  11   12
Affiliations
Review

Are Community Acquired Respiratory Viral Infections an Underestimated Burden in Hematology Patients?

Cristian-Marian Popescu et al. Microorganisms. .

Abstract

Despite a plethora of studies demonstrating significant morbidity and mortality due to community-acquired respiratory viral (CRV) infections in intensively treated hematology patients, and despite the availability of evidence-based guidelines for the diagnosis and management of respiratory viral infections in this setting, there is no uniform inclusion of respiratory viral infection management in the clinical hematology routine. Nevertheless, timely diagnosis and systematic management of CRV infections in intensively treated hematology patients has a demonstrated potential to significantly improve outcome. We have briefly summarized the recently published data on CRV infection epidemiology, as well as guidelines on the diagnosis and management of CRV infections in patients intensively treated for hematological malignancies. We have also assessed available treatment options, as well as mentioned novel agents currently in development.

Keywords: community respiratory viruses; hematological malignancy; intensive chemotherapy; respiratory viral infections; stem cell transplantation.

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Conflict of interest statement

The authors declare no conflict of interest.

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