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Editorial
. 2019 Dec;215(6):697-698.
doi: 10.1192/bjp.2019.194.

A possible role for sarcosine in the management of schizophrenia

David Curtis  1
Affiliations
Editorial

A possible role for sarcosine in the management of schizophrenia

David Curtis. Br J Psychiatry. 2019 Dec.

Abstract

Sarcosine, which is freely sold as a dietary supplement, has pharmacological activity to boost functioning of the glutamatergic N-methyl-d-aspartate receptor (NMDAR) and hence it is a biologically rational treatment for schizophrenia. The small number of studies carried out to date provide some evidence for its efficacy and psychiatrists could consider suggesting its use to their patients.

Keywords: Sarcosine; glutamate; glycine; pharmacology; schizophrenia.

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  • Author's reply.
    Curtis D. Curtis D. Br J Psychiatry. 2020 Nov;217(5):653. doi: 10.1192/bjp.2020.173. Br J Psychiatry. 2020. PMID: 33100243 No abstract available.
  • Sarcosine in the management of schizophrenia.
    Brennan D. Brennan D. Br J Psychiatry. 2020 Nov;217(5):653. doi: 10.1192/bjp.2020.172. Br J Psychiatry. 2020. PMID: 33100244 No abstract available.

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