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. 2020 Feb:217:189-191.e2.
doi: 10.1016/j.jpeds.2019.09.051. Epub 2019 Nov 2.

Association between Serum Ferritin and Cognitive Function in Early Childhood

Patricia C Parkin  1 , Christine Koroshegyi  2 , Eva Mamak  2 , Cornelia M Borkhoff  3 , Catherine S Birken  4 , Jonathon L Maguire  5 , Kevin E Thorpe  5 ; TARGet Kids! Collaboration
Collaborators, Affiliations

Association between Serum Ferritin and Cognitive Function in Early Childhood

Patricia C Parkin et al. J Pediatr. 2020 Feb.

Abstract

In infants 1-3 years of age, we found higher serum ferritin values associated with higher cognitive function, as measured by the Mullen Scales of Early Learning (P = .02 for the nonlinear relationship). A serum ferritin of 17 μg/L corresponded to the maximum level of cognition, beyond which there was no meaningful improvement. TRIAL REGISTRATION: Clinicaltrials.gov NCT01481766 and NCT01869530.

Keywords: hemoglobin; iron deficiency.

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