Cranial Nerve Stimulation for Olfaction (Cranial Nerve 1)
- PMID: 31685237
- DOI: 10.1016/j.otc.2019.09.014
Cranial Nerve Stimulation for Olfaction (Cranial Nerve 1)
Abstract
Like sensory maps in other systems, the sense of smell has an organizational structure based on converging projections of olfactory receptor neurons containing unique odorant receptors onto the olfactory bulb in synaptic aggregations termed glomeruli. This organizational structure provides the potential for electrical stimulation and restoration of smell. Prior animal and human studies support the feasibility of an olfactory stimulation device, encouraging ongoing work in development of olfactory implants.
Keywords: Electrode; Implant; Olfactory bulb; Restoration; Smell.
Copyright © 2019 Elsevier Inc. All rights reserved.
Similar articles
-
Interglomerular center-surround inhibition shapes odorant-evoked input to the mouse olfactory bulb in vivo.J Neurophysiol. 2006 Mar;95(3):1881-7. doi: 10.1152/jn.00918.2005. Epub 2005 Nov 30. J Neurophysiol. 2006. PMID: 16319205
-
Odorant receptors in the formation of the olfactory bulb circuitry.Physiology (Bethesda). 2012 Aug;27(4):200-12. doi: 10.1152/physiol.00015.2012. Physiology (Bethesda). 2012. PMID: 22875451 Review.
-
Optical imaging of odorant representations in the mammalian olfactory bulb.Neuron. 1999 Jul;23(3):499-511. doi: 10.1016/s0896-6273(00)80803-x. Neuron. 1999. PMID: 10433262
-
Odorant receptors signaling instructs the development and plasticity of the glomerular map.Neural Plast. 2015;2015:975367. doi: 10.1155/2015/975367. Epub 2015 Jan 20. Neural Plast. 2015. PMID: 25688305 Free PMC article. Review.
-
Representation of odorants by receptor neuron input to the mouse olfactory bulb.Neuron. 2001 Nov 20;32(4):723-35. doi: 10.1016/s0896-6273(01)00506-2. Neuron. 2001. PMID: 11719211
Cited by
-
Therapies for Olfactory Dysfunction - an Update.Curr Allergy Asthma Rep. 2022 Mar;22(3):21-28. doi: 10.1007/s11882-022-01028-z. Epub 2022 Jan 24. Curr Allergy Asthma Rep. 2022. PMID: 35072929 Free PMC article. Review.
-
Olfactory neuropathology in Alzheimer's disease: a sign of ongoing neurodegeneration.BMB Rep. 2021 Jun;54(6):295-304. doi: 10.5483/BMBRep.2021.54.6.055. BMB Rep. 2021. PMID: 34162463 Free PMC article. Review.
-
Surgical Approaches for Possible Positions of an Olfactory Implant to Stimulate the Olfactory Bulb.ORL J Otorhinolaryngol Relat Spec. 2023;85(5):253-263. doi: 10.1159/000529563. Epub 2023 Mar 30. ORL J Otorhinolaryngol Relat Spec. 2023. PMID: 36996786 Free PMC article.
-
Rehabilitation Evaluation of Hemiplegic Patients with Anterior Circulation Cerebral Infarction Based on Cranial Magnetic Stimulation.J Healthc Eng. 2021 Jul 29;2021:7868419. doi: 10.1155/2021/7868419. eCollection 2021. J Healthc Eng. 2021. Retraction in: J Healthc Eng. 2023 Nov 1;2023:9814813. doi: 10.1155/2023/9814813. PMID: 34367539 Free PMC article. Retracted.
-
International consensus statement on allergy and rhinology: Olfaction.Int Forum Allergy Rhinol. 2022 Apr;12(4):327-680. doi: 10.1002/alr.22929. Int Forum Allergy Rhinol. 2022. PMID: 35373533 Free PMC article. Review.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources