Neuronal activity in the monkey striatum during the initiation of movements

Abstract

The sources of afferent input to the striatum (caudate nucleus and putamen) suggest that this structure may be engaged in neuronal processes related to the initiation of movement. We found that 26% of 508 neurons in both parts of the striatum were activated during the presentation of visual signals which prepared the animals for the execution or withholding of individual arm reaching movements. In a second task, 20% of 382 striatal neurons were activated up to 3 s before self-initiated, non automatic and purposive arm movements which were performed in the complete absence of phasic external stimuli. The data demonstrate an involvement of the striatum in externally and internally generated processes which are related to presetting mechanisms during the initiation of behavioral acts.