Signal of potentially protective drug-drug interactions from spontaneous reporting systems: proceed with caution

Affiliations

¹ Pharmacology Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
² University of Bordeaux, U657, 33000, Bordeaux, France.
³ INSERM U657, 33000, Bordeaux, France.
⁴ CIC Bordeaux CICI1401, 33000, Bordeaux, France.
⁵ Unit of Metabolic Diseases and Clinical Dietetics, Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Via Massarenti 9, 40138, Bologna, Italy.
⁶ Pharmacology Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy. emanuel.raschi@unibo.it.

Comment

Ippazio Cosimo Antonazzo et al. Acta Diabetol. 2020 Jan.

. 2020 Jan;57(1):115-116.

doi: 10.1007/s00592-019-01441-3. Epub 2019 Nov 6.

¹ Pharmacology Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy.
² University of Bordeaux, U657, 33000, Bordeaux, France.
³ INSERM U657, 33000, Bordeaux, France.
⁴ CIC Bordeaux CICI1401, 33000, Bordeaux, France.
⁵ Unit of Metabolic Diseases and Clinical Dietetics, Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Via Massarenti 9, 40138, Bologna, Italy.
⁶ Pharmacology Unit, Department of Medical and Surgical Sciences, Alma Mater Studiorum, University of Bologna, Via Irnerio, 48, 40126, Bologna, Italy. emanuel.raschi@unibo.it.

No abstract available

Comment on

Myopathy with DPP-4 inhibitors and statins in the real world: investigating the likelihood of drug-drug interactions through the FDA adverse event reporting system.
Antonazzo IC, Poluzzi E, Forcesi E, Salvo F, Pariente A, Marchesini G, De Ponti F, Raschi E. Antonazzo IC, et al. Acta Diabetol. 2020 Jan;57(1):71-80. doi: 10.1007/s00592-019-01378-7. Epub 2019 Jun 15. Acta Diabetol. 2020. PMID: 31203438
A missed protective drug-drug interaction of DPP-4 inhibitors and statins on myopathy risk.
Kuss O, Rathmann W. Kuss O, et al. Acta Diabetol. 2020 Jan;57(1):113-114. doi: 10.1007/s00592-019-01440-4. Epub 2019 Nov 6. Acta Diabetol. 2020. PMID: 31691868 No abstract available.