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. 2019 Aug 20:33:309.
doi: 10.11604/pamj.2019.33.309.17547. eCollection 2019.

Adherence to insulin therapy and associated factors among patients with diabetes mellitus in public hospitals of Central Zone of Tigray, Ethiopia, 2018: a cross-sectional study

Teklewoini Mariye  1 , Alem Girmay  1 , Tsyion Birhanu  1 , Hagos Tasew  2 , Girmay Teklay  2 , Zeray Baraki  2 , Hadgu Gerensea  2 , Tewolde Teklu  3 , Gebrewahed Bezabeh  4
Affiliations

Adherence to insulin therapy and associated factors among patients with diabetes mellitus in public hospitals of Central Zone of Tigray, Ethiopia, 2018: a cross-sectional study

Teklewoini Mariye et al. Pan Afr Med J. .

Abstract

Introduction: Adherence to insulin therapy is a critical factor for adequate control of diabetes mellitus. Despite the multiple well-known benefits of adherence to insulin therapy, poor adherence remains to be a common cause of diabetes mellitus-related complications. A better management of diabetes mellitus requires determining the level of patient adherence and identifying why non-adherence to insulin therapy occurs. Therefore, this study was designed to assess the level of adherence to insulin therapy and associated factors among diabetes mellitus patients.

Methods: The study was conducted from May 1 to July 1, 2018, using a cross-sectional study design. Interviewer-administered questionnaire was employed for data collection and systematic random sampling technique was used to select study participants. The collected data were entered using Epi data version 3.1.1 and exported to SPSS version 22 for analysis. Logistic analysis was carried out to check the level of association between adherence to insulin therapy and the independent variables with significance level of 0.05 at 95% confidence interval.

Results: 273 respondents were selected with a 100% response rate. Near to one-fourth (24.2%) of the respondents were adherent to their insulin therapy. The study revealed that good knowledge of diabetes mellitus [AOR=6.51; 95% CI [1.58, 26.71], age [>30 years] [AOR=2.63; 95% CI [1.27, 5.42], knowledge regarding insulin self-injection [AOR=4.21; 95%CI [1.06,16.65], favorable attitude towards insulin injection [AOR=2.14; 95% CI [1.04,4.41], free-of-cost insulin therapy [AOR= 4.62, 95% CI [1.06,16.65], having of glucometer at home [AOR= 2.82, 95% CI [1.12,7.09], and being a member of Ethiopian diabetic association [AOR= 5.41, 95% CI [2.31,12.64] were found to significantly affect adherence to insulin therapy.

Conclusion: Nearly one-fourth of the study participants were adherent to their insulin therapy. Good knowledge and favorable attitude towards insulin injection, good knowledge regarding diabetes mellitus, being a member of the Ethiopian Diabetes Association, age greater than thirty years old, free-of-cost insulin therapy and having glucometer at home were found to be significant predictors of adherence to insulin therapy.

Keywords: Adherence; Ethiopia; diabetes mellitus; insulin therapy.

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Conflict of interest statement

The authors declare no competing interests.

References

    1. Landon BE, Zaslavsky AM, Souza J, Ayanian JZ. Trends in diabetes treatment and monitoring among Medicare beneficiaries. J Gen Intern Med. 2018;33(4):471–80. - PMC - PubMed
    1. Cho NH, Shaw JE, Karuranga S, Huang Y, da Rocha Fernandes JD, Ohlrogge AW, et al. IDF Diabetes Atlas: global estimates of diabetes prevalence for 2017 and projections for 2045. Diabetes Res Clin Pract. 2018;138:271–81. - PubMed
    1. Association AD 9. Cardiovascular disease and risk management: standards of medical care in diabetes. Diabetes care. 2018;41(Supplement 1):S86–S104. - PubMed
    1. Association AD. Standards of medical care in diabetes abridged for primary care providers. Clinical diabetes: a publication of the ADA. 2016;34(1):3–21. - PMC - PubMed
    1. Monnier L, Colette C, Owens D. The application of simple metrics in the assessment of glycaemic variability. Diabetes Obes Metab. 2018 Sep;44(4):313–319. - PubMed