Heterogeneity Between Genetic Variants as a Proxy for Pleiotropy in Mendelian Randomization-Reply

Milad Nazarzadeh^{1

2

3}, Kazem Rahimi^{1

2

4}

Affiliations

¹ The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
² Deep Medicine, Oxford Martin School, University of Oxford, United Kingdom.
³ Collaboration Center of Meta-Analysis Research, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
⁴ NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

Comment

Milad Nazarzadeh et al. JAMA Cardiol. 2020.

. 2020 Jan 1;5(1):108.

doi: 10.1001/jamacardio.2019.4284.

Milad Nazarzadeh^{1

2

3}, Kazem Rahimi^{1

2

4}

¹ The George Institute for Global Health, University of Oxford, Oxford, United Kingdom.
² Deep Medicine, Oxford Martin School, University of Oxford, United Kingdom.
³ Collaboration Center of Meta-Analysis Research, Torbat Heydariyeh University of Medical Sciences, Torbat Heydariyeh, Iran.
⁴ NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.

No abstract available

Comment on

Systolic Blood Pressure and Risk of Valvular Heart Disease: A Mendelian Randomization Study.
Nazarzadeh M, Pinho-Gomes AC, Smith Byrne K, Canoy D, Raimondi F, Ayala Solares JR, Otto CM, Rahimi K. Nazarzadeh M, et al. JAMA Cardiol. 2019 Aug 1;4(8):788-795. doi: 10.1001/jamacardio.2019.2202. JAMA Cardiol. 2019. PMID: 31290937 Free PMC article.
Heterogeneity Between Genetic Variants as a Proxy for Pleiotropy in Mendelian Randomization.
Gill D. Gill D. JAMA Cardiol. 2020 Jan 1;5(1):107-108. doi: 10.1001/jamacardio.2019.4281. JAMA Cardiol. 2020. PMID: 31693062 No abstract available.