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Case Reports
. 2020 Feb;45(2):e106-e107.
doi: 10.1097/RLU.0000000000002818.

18F-FDG PET/CT in Graft Versus Host Disease-Associated Polymyositis

Apurva Sood  1 , Alka Rani Khadwal  2 , Tinu Lukose  1 , Rajender Kumar  1 , Harmandeep Singh  1 , Amanjit Bal  3 , Bhagwant Rai Mittal  1
Affiliations
Case Reports

18F-FDG PET/CT in Graft Versus Host Disease-Associated Polymyositis

Apurva Sood et al. Clin Nucl Med. 2020 Feb.

Abstract

Graft versus host disease (GVHD) is the most frequent and serious complication of allogenic hematopoietic stem cell transplant. Polymyositis is a rare neuromuscular manifestation of GVHD, which often responds well to corticosteroid and immunosuppression therapy. We present a case of a 38-year-old man with a known case of mixed-phenotype acute leukemia after hematopoietic stem cell transplant presenting with GVHD-associated polymyositis. F-FDG PET/CT done in this case not only helped in the detection of the muscle involvement but also helped in obtaining precise muscle sample for histopathological diagnosis using PET-guided biopsy.

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References

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