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Review
. 2019 Nov 6;19(1):1057.
doi: 10.1186/s12885-019-6293-x.

Giant cell tumor of tendon sheath in the wrist that damaged the extensor indicis proprius tendon: a case report and literature review

Qingfang Zhao  1 , Hui Lu  2
Affiliations
Review

Giant cell tumor of tendon sheath in the wrist that damaged the extensor indicis proprius tendon: a case report and literature review

Qingfang Zhao et al. BMC Cancer. .

Abstract

Background: Giant cell tumor of the tendon sheath (GCTTS) is a benign soft tissue (synovial membrane) tumor that rarely involves the hands or wrists. And Tendon impairment caused by GCTTS is extremely rare.

Case presentation: Here, we reported a case of a 60-year-old female with a 10-year history of gradually increasing mass in her left dorsal wrist. The EIP tendon was partially impaired by the mass.The patient was treated with surgical excision of the mass and reconstruction of the EIP tendon. The histopathological examination suggested the presence of GCTTS. After surgery, the patient had adequate functional recovery and no tumor recurrence after 2 years' follow-up.

Conclusion: GCTTS in hands and wrists rarely damages the tendon. Early diagnosis and proactive interventions may likely contribute to good prognostic outcomes.

Keywords: Extensor indicis proprius tendon(EIP tendon); Giant cell tumor of tendon sheath(GCTTS); Impairment of tendon.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
MRI (a,b,c) reveals a 18 × 6× 5 mm spindle-like mass,encircles the extensor indicis proprius tendon in her left dorsal wrist.The lesion shows iso-indensity on T1 image (1a),while it shows hyperintense signal on T1WI with fat suppression(b: axial plane; c: sagittal plane) and T2WI with fat suppression (d).On T2WI with fat suppression (d), we can see the mass (shows hyperintense signal in the center and iso-indensity in the peripheral) attached to the EIP tendon(shows hypointense signal)
Fig. 2
Fig. 2
Intraoperative photograph (a) shows that the lesion was at the surface of the extensor indicis proprius tendon and that the tendon was partly infiltrated; (b and c): even though the tumor had a capsule, it partly infiltrated and destroyed the tendon
Fig. 3
Fig. 3
Pathological examination of the tumor using hematoxylin–eosin stain. a Multinucleated giant cells were distributed in the interstitial tissue; (b) the synovial mononuclear cells were pervaded
Fig. 4
Fig. 4
Pathological examination of tumor using immunohistochemistry staining. a Monocytes with positive CD68. b Monocytes with positive Ki-67
See this image and copyright information in PMC

References

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