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. 1979 Dec;54(12):954-7.
doi: 10.1136/adc.54.12.954.

Lymphocyte changes in beta-thalassaemia major

S Musumeci, G Schiliro, M A Romeo, A Sciotto, A Rosalba, G Pizzarelli

Lymphocyte changes in beta-thalassaemia major

S Musumeci et al. Arch Dis Child. 1979 Dec.

Abstract

Lymphocyte subpopulations were studied in 20 hypertransfused patients with beta-thalassaemia major, some of whom had been splenectomised. B-lymphocytes were normal but T-lymphocytes were decreased in all patients. The T-cell count was lower in the splenectomised patients than in the nonsplenectomised ones. In the former, the active rosette-forming lymphocytes were also diminished, but the difference was not significant. In all patients the percentage of null cells was greater and the activity of K-cells increased compared with controls.

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References

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