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Review
. 2019 Jun 4;5(4):256-260.
doi: 10.1016/j.ijwd.2019.05.009. eCollection 2019 Sep.

Dermatomyositis in patients with autoimmune blistering diseases

Aikaterini Patsatsi  1   2 , David R Pearson  1   2 , Victoria P Werth  1   2
Affiliations
Review

Dermatomyositis in patients with autoimmune blistering diseases

Aikaterini Patsatsi et al. Int J Womens Dermatol. .

Abstract

It is common for multiple autoimmune diseases to occur in the same patient. However, autoimmune blistering diseases (AIBD) do not commonly associate with dermatomyositis (DM). We performed a literature review and found 12 previous reports that may be attributed to misdiagnosis, underreporting, or true rarity of association. Herein, we present a case of pemphigus vulgaris and a case of mucous membrane pemphigoid associated with DM and review the related literature. AIBD-associated interstitial lung disease, genetic predisposition, potential environmental triggers of both AIBD and DM, drug-related triggers, and paraneoplastic processes are discussed. Dermatologists must be vigilant for a second autoimmune disease in patients with AIBD that may have therapeutic implications.

Keywords: Dermatomyositis; autoimmune; blistering; interstitial lung disease; pemphigoid; pemphigus.

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Figures

Fig. 1
Fig. 1
Dilated capillary loops and hemorrhage on the proximal nail folds (Case 1).
Fig. 2
Fig. 2
Prominent erythema on the extensor elbows and overlying the knuckles (Gottron’s sign) (Case 2).
See this image and copyright information in PMC

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