Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Dec;86(12):1142-1145.
doi: 10.1007/s12098-019-03094-0. Epub 2019 Nov 7.

Predictors of Mortality in Children Admitted to the Pediatric Intensive Care Unit with Acute Gastroenteritis with Severe Dehydration

Man Singh  1 , Jhuma Sankar  2 , Arvind Kumar  1 , U Vijay Kumar  1 , Rakesh Lodha  1 , Sushil K Kabra  1
Affiliations

Predictors of Mortality in Children Admitted to the Pediatric Intensive Care Unit with Acute Gastroenteritis with Severe Dehydration

Man Singh et al. Indian J Pediatr. 2019 Dec.

Abstract

The objective of the present study was to identify risk factors for mortality at admission in children admitted to the Pediatric Intensive Care Unit (PICU) with acute gastroenteritis (AGE) with severe dehydration and shock. This was a retrospective chart review of all cases of AGE with severe dehydration and shock admitted to the PICU from 2012 to 2017. Children who died during hospital stay were compared with those who survived. A total of 62 children were admitted with AGE to the PICU during this period. Twenty-four children (39%) died. The following variables were found to be significantly associated with death on univariate analysis: clinical pallor (p = 0.01), thrombocytopenia (p = 0.018), elevated leucocyte count (p = 0.02), hypoalbuminemia (p = 0.02) and severe acute malnutrition (SAM) (p = 0.04). On multivariate analysis, only hypoalbuminemia {RR [95% CI: 2.6 (1.27 to 9.21)]; 0.039} and SAM {RR [95% CI: 4.9 (1.12 to 10)]; 0.045} remained statistically significant. Children admitted with severe dehydration and shock had high mortality rates. These children were a sicker subset with probable sepsis. Severe acute malnutrition and hypoalbuminemia were associated with increased risk of death in these patients.

Keywords: Acute gastroenteritis; Diarrhea; Hypoalbuminemia; Oral rehydration solution; Shock.

PubMed Disclaimer

References

    1. Acta Paediatr. 2011 Dec;100(12):e275-9 - PubMed
    1. Nutr Rev. 2008 Sep;66(9):487-505 - PubMed
    1. Glob Pediatr Health. 2017 Mar 30;4:2333794X17696685 - PubMed
    1. Lancet Child Adolesc Health. 2018 Jul;2(7):516-524 - PubMed
    1. Trans R Soc Trop Med Hyg. 1991 Sep-Oct;85(5):685-7 - PubMed

MeSH terms