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Editorial
. 2020 Mar 1;116(3):470-472.
doi: 10.1093/cvr/cvz273.

Hearts and Hands: the good, the bad, and the ugly

Jop H van Berlo  1   2   3 , Daniel J Garry  1   2   3   4   5
Affiliations
Editorial

Hearts and Hands: the good, the bad, and the ugly

Jop H van Berlo et al. Cardiovasc Res. .
No abstract available

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Figures

Figure 1
Figure 1
Hand1 is an essential transcriptional regulator that governs cardiac morphogenesis. Left panel: Is a scanning electron micrograph of a developing murine heart at E9.5 pseudocoloured red for the expression domain of Hand1. Right panel: Hand1 expression results in normal cardiac morphogenesis. However, if cardiac expression of Hand1 during development is perturbed, the study by Firulli et al. demonstrated a phenotype that results in ventricular septal defects, increased trabeculation, and an absence of chordae tendineae associated with the mitral valve.
See this image and copyright information in PMC

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References

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