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. 2019 Dec;42(12):843-844.
doi: 10.1016/j.tins.2019.10.005. Epub 2019 Nov 6.

Is There a Hemispheric Disconnect in Neurodevelopmental Disorders?

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Is There a Hemispheric Disconnect in Neurodevelopmental Disorders?

Jacob Ellegood. Trends Neurosci. 2019 Dec.

Abstract

The CYFIP1 gene has been linked to autism and schizophrenia and, while there is a noted heterogeneity, both have been characterized to be disorders of connectivity. Recent studies by Dominquez-Iturza et al. and Silva et al. provide direct evidence for CYFIP1 in functional and structural connectivity in the brain.

Keywords: Cyfip1; autism; diffusion tensor imaging; magnetic resonance imaging; mouse; schizophrenia.

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