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Randomized Controlled Trial
. 2020 Mar;24(3):536-543.
doi: 10.1002/ejp.1503. Epub 2019 Nov 25.

Analgesic efficacy of 10% lidocaine spray during nasoenteral catheterization: Randomized triple-blind trial

Amanda Santos de Oliveira  1 , Caíque Jordan Nunes Ribeiro  1 , Aline Láyra Carvalho Oliveira  2 , Viviane Oliveira de Sousa Correia  2 , Jonas Santana Pinto  2 , Evando Santos-Júnior  3 , Maria do Carmo de Oliveira Ribeiro  1   2
Affiliations
Randomized Controlled Trial

Analgesic efficacy of 10% lidocaine spray during nasoenteral catheterization: Randomized triple-blind trial

Amanda Santos de Oliveira et al. Eur J Pain. 2020 Mar.

Abstract

Background: Pain is a common experience during nasoenteral catheterization. Although the procedure causes discomfort and distress to patients, procedural pain remains neglected and undertreated.

Objective: To evaluate the analgesic efficacy of the use of 10% lidocaine spray during nasoenteral catheterization.

Method: A randomized, triple-blind trial of 50 patients was performed. The patients were randomly assigned to two groups: an intervention group (IG), in which 10% lidocaine spray combined with 2% lidocaine gel was used, and a control group (CG), in which a saline solution spray combined with 2% lidocaine gel was used. Pain and discomfort were assessed during and after nasoenteral catheterization using numerical rating scale (NRS) and the visual analogue scale (VAS), respectively.

Results: Intervention group participants reported lower pain scores during (0.20 ± 0.71 vs. 5.00 ± 2.84, p < .001; |d| = -0.677) and after (0.00 ± 0.00 vs. 2.80 ± 2.83, p < .001; |d| = -0.718) nasoenteral catheterization compared to the CG.

Conclusion: Spraying 10% lidocaine spray before nasoenteral catheterization was most effective for relieving discomfort and pain, with lower pain and discomfort recorded in NRS and VAS. Topical administration of 10% lidocaine spray is therefore a suggested measure for procedural pain relief related to nasoenteral catheterization.

Significance: The use of 10% lidocaine spray was more effective in relieving procedural pain and discomfort during nasoenteral catheterization. Patients who received 10% lidocaine spray registered lower discomfort and pain scores than those from 2% lidocaine gel group; there were less complications among patients in the IG.

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