Copper involvement in glutamatergic transmission in physiology and disease as revealed by magnetoencephalography/electroencephalography (MEG/EEG) studies

Affiliations

¹ IRCCS Istituto Centro San Giovanni di Dio-Fatebenefratelli, Brescia, 25125, Italy. rosanna.squitti@afar.it.
² Institute of Neuroscience, CNR, Via Vanvitelli 32, 20129, Milan, Italy.
³ Laboratory of Pharmacology and Brain Pathology, Neuro Center, Humanitas Clinical and Research Center-IRCCS, via Manzoni 56, 20089, Rozzano, MI, Italy.
⁴ Department of Laboratory Medicine, Research and Development Division, Fatebenefratelli Hospital, Isola Tiberina, Rome, Italy.
⁵ Let's-ISTC-CNR and IRCCS Policlinico Gemelli, Rome, Italy.

Rosanna Squitti et al. Aging Clin Exp Res. 2021 Jul.

. 2021 Jul;33(7):2023-2026.

doi: 10.1007/s40520-019-01402-4. Epub 2019 Nov 9.

¹ IRCCS Istituto Centro San Giovanni di Dio-Fatebenefratelli, Brescia, 25125, Italy. rosanna.squitti@afar.it.
² Institute of Neuroscience, CNR, Via Vanvitelli 32, 20129, Milan, Italy.
³ Laboratory of Pharmacology and Brain Pathology, Neuro Center, Humanitas Clinical and Research Center-IRCCS, via Manzoni 56, 20089, Rozzano, MI, Italy.
⁴ Department of Laboratory Medicine, Research and Development Division, Fatebenefratelli Hospital, Isola Tiberina, Rome, Italy.
⁵ Let's-ISTC-CNR and IRCCS Policlinico Gemelli, Rome, Italy.

No abstract available

Keywords: Alzheimer’s disease; Copper; Glutammate; Magnetoencephalography/electroencephalography (MEG/EEG) synapse; Mild cognitive impairment.

References

1. Sensi SL, Granzotto A, Siotto M et al (2018) Copper and zinc dysregulation in Alzheimer’s disease. Trends Pharmacol Sci 39:1049–1063. https://doi.org/10.1016/j.tips.2018.10.001 - DOI - PubMed
1. Telianidis J, Hung YH, Materia S et al (2013) Role of the P-Type ATPases, ATP7A and ATP7B in brain copper homeostasis. Front Aging Neurosci 5:1–11. https://doi.org/10.3389/fnagi.2013.00044 - DOI
1. McCann CJ, Jayakanthan S, Siotto M et al (2019) Single nucleotide polymorphisms in the human ATP7B gene modify the properties of the ATP7B protein. Metallomics 11:1128–1139. https://doi.org/10.1039/c9mt00057g - DOI - PubMed - PMC
1. Salustri C, Tecchio F, Zappasodi F et al (2013) Sensorimotor cortex reorganization in Alzheimer’s disease and metal dysfunction: a MEG study. Int J Alzheimers Dis 63831:1–8. https://doi.org/10.1155/2013/638312 - DOI
1. Tecchio F, Assenza G, Zappasodi F et al (2011) Glutamate-mediated primary somatosensory cortex excitability correlated with circulating copper and ceruloplasmin. Int J Alzheimers Dis 292593:1–8. https://doi.org/10.4061/2011/292593 - DOI