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. 2019 May-Jun;12(3):182-188.
doi: 10.5005/jp-journals-10005-1616.

A Regenerative Approach for Root Canal Treatment of Mature Permanent Teeth: Comparative Evaluation with 18 Months Follow-up

Preeti Jha  1 , Mandeep S Virdi  1 , Suman Nain  1
Affiliations

A Regenerative Approach for Root Canal Treatment of Mature Permanent Teeth: Comparative Evaluation with 18 Months Follow-up

Preeti Jha et al. Int J Clin Pediatr Dent. 2019 May-Jun.

Abstract

Aim: SealBio is a novel technique which stimulates the periradicular cells to deposit a biological barrier at the root apex by inducing healing and regeneration. This clinical trial was undertaken to compare the outcome of teeth treated with the SealBio and the obturation technique.

Materials and methods: Thirty patients met the inclusion criteria and consented to participate in the study. Patients were randomly assigned to the SealBio and the obturation group. The time taken for both the techniques and periapical healing was evaluated. The patients of both the groups were evaluated at 6, 12, and 18 months follow up. The periapical index (PAI) was the primary outcome measure to check the apical bone density and healing. The secondary outcome measure was the presence/absence of signs and symptoms. The final outcome measure was the sum of the primary and secondary outcome measures.

Results and conclusion: The time taken to perform endodontic treatment with the SealBio technique was significantly lesser than that of obturation. Both groups showed equally favorable outcomes at the end of 18 months without any statistically significant differences.

Clinical significance: The results of the present study have demonstrated that SealBio technique gives similar results as that of conventional gutta-percha obturation. The shortcomings of obturation such as difficulty in obtaining a fluid-tight seal and difficulty in obturating tortuous canals can be overcome by the SealBio method. The SealBio method is cost effective, less technique sensitive, and takes lesser chair time.

How to cite this article: Jha P, Virdi MS, et al. A Regenerative Approach for Root Canal Treatment of Mature Permanent Teeth: Comparative Evaluation with 18 Months Follow-up. Int J Clin Pediatr Dent 2019;12(3):182-188.

Keywords: Apical periodontitis; Mature teeth; Necrotic pulp; Periapical abscess; Regenerative endodontics; SealBio.

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Conflict of interest statement

Source of support: Nil Conflict of interest: None

Figures

Fig. 1
Fig. 1
Graphical presentation of the mean PAI scores of groups I and II preoperatively and at 6, 12, and 18 months follow-up. Actual numbers from which a graph is drawn
Figs 2A to E
Figs 2A to E
(A) Preoperative radiograph of #7 and #8 showing large periapical radiolucent lesion; (B) Immediate postoperative radiograph after the SealBio procedure; (C) 6-months follow-up; (D) 12-months follow-up; (E) 18-months follow-up
Figs 3A to E
Figs 3A to E
(A) Preoperative radiograph of #30 showing well-defined periapical radiolucent lesion at the mesial root; (B) Immediate postoperative radiograph after the SealBio procedure; (C) 6-months follow-up; (D) 12-months follow-up; (E) 18-months follow-up
Figs 4A to E
Figs 4A to E
(A) Preoperative radiograph of #8 and #9 showing periapical radiolucent lesion; (B) Immediate postoperative radiograph after obturation; (C) 6-months follow-up; (D) 12-months follow-up; (E) 18-months follow-up
Figs 5A to E
Figs 5A to E
(A) Preoperative radiograph of #30 showing well defined periapical radiolucent lesion; (B) Immediate postoperative radiograph after the obturation procedure; (C) 6-months follow-up; (D) 12-months follow-up; (E) 18-months follow-up
See this image and copyright information in PMC

References

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