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Review
. 2019;135(5):85-91.
doi: 10.17116/oftalma201913505185.

[Mitochondrial biogenesis in hereditary optic neuropathies]

[Article in Russian]
N L Sheremet  1 , N A Andreeva  1 , M S Shmel'kova  1 , P G Tsigankova  2
Affiliations
Review

[Mitochondrial biogenesis in hereditary optic neuropathies]

[Article in Russian]
N L Sheremet et al. Vestn Oftalmol. 2019.

Abstract
in English, Russian

The article offers a review of mitochondrial biogenesis in hereditary optic neuropathies. It covers the mechanisms of mitochondrial biogenesis, factors affecting it and tools for mitochondrial turnover assessment.

Представлен обзор научных публикаций, посвященных исследованию митохондриального биогенеза при наследственных оптических нейропатиях. Рассмотрены особенности механизмов митохондриального биогенеза, факторы, оказывающие влияние на процессы биогенеза, а также способы определения, оценки и анализа жизненного цикла митохондрий.

Keywords: Leber hereditary optic neuropathy; estrogens; mitochondrial biogenesis; mitochondrial optical neuropathies; mitochondrial respiratory chain; mtDNA mutations; optic nerve; oxidative stress; retinal ganglion cell; toxic neuropathies.

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