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Review
. 2019 Dec 20;25(6):289-295.
doi: 10.5761/atcs.ra.19-00070. Epub 2019 Nov 13.

Pulmonary Metastasectomy for Germ Cell Tumors

Armin Farazdaghi  1 , David J Vaughn  2 , Sunil Singhal  3
Affiliations
Review

Pulmonary Metastasectomy for Germ Cell Tumors

Armin Farazdaghi et al. Ann Thorac Cardiovasc Surg. .

Abstract

Germ cell tumors (GCTs) are the most common malignancy among young men in the United States. Although prognosis is favorable and response to cisplatin-based chemotherapy regimens is good, 10%-20% of patients with thoracic metastases require surgical management following completion of chemotherapy. Pulmonary metastasectomy (PM) has been employed for GCT patients with lung metastases for several decades. Outcomes have been excellent thus far. However, there have been no randomized controlled trials of PM in GCT and, as new surgical techniques are developed, there is variability in management. This article reviews the existing data on current management of pulmonary metastases in GCT, with attention paid to timing of surgery, surgical approaches, and complications.

Keywords: germ cell tumor; lung metastases; metastatic germ cell tumor; pulmonary metastasectomy; secondary lung cancer.

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