Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2019 Oct 23;8(1):192-198.
doi: 10.1080/21556660.2019.1684926. eCollection 2019.

Characteristics of patients with dyslipidemia treated in routine care setting in China

Gordon Liu  1 , Jason Shepherd  2 , Pratik Rane  3 , Zhongyun Zhao  3 , Hollie Bailey  2 , Nathan Williams  2 , Yi Qian  3
Affiliations

Characteristics of patients with dyslipidemia treated in routine care setting in China

Gordon Liu et al. J Drug Assess. .

Abstract

Objective: To describe characteristics of patients with dyslipidemia treated in routine care in China overall and stratified by diabetes and atherosclerotic cardiovascular disease (ASCVD). Methods: This study used data from a cross-sectional survey conducted in China in 2017 under the Dyslipidemia Disease Specific Programme (DSP). Each surveyed physician provided information including demographics, dyslipidemia diagnosis and treatment history, lab values on at least 8 patients currently treated for dyslipidemia with oversampling of patients with ASCVD or diabetes mellitus diagnosis at the time of survey. A related patient survey assessed treatment adherence and satisfaction. Results: This study included 195 physicians (40 endocrinologists, 75 internists, 80 cardiologists) who provided data on 1870 patients (852 with diabetes; 1018 patients without diabetes). Among patients with diabetes, 279 had ASCVD and 573 did not (non-ASCVD). In the diabetic population, patients with ASCVD were older (67.3 vs. 62.1 years), more often had caregiver support (34 vs. 14%), and had higher average LDL-C at diagnosis (172.4 vs. 167.4 mg/dL) compared to their non-ASCVD counterparts. Findings were similar for non-diabetic patients (ASCVD: 323 patients; non-ASCVD: 695) patients. In all four subgroups, 46-54% of patients reported low treatment adherence, and fewer than half expressed satisfaction with their cholesterol control, and 2-5% had LDL-C < 70 mg/dL at their most recent assessment. Conclusions: Among patients with dyslipidemia, those with ASCVD had higher LDL-C levels than patients without ASCVD, and many required caregiving. Low levels of treatment adherence, LDL-C control, and patient satisfaction suggest opportunities to improve care for Chinese patients with dyslipidemia.

Keywords: China; Dyslipidemia; atherosclerotic cardiovascular disease; diabetes; hyperlipidemia.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Hyperlipidemia diagnoses among patients stratified by diabetes and ASCVD status. ASCVD, atherosclerotic cardiovascular disease. Combined hyperlipidemia: hyperlipidemia/hypertriglyeridemia
Figure 2.
Figure 2.
Self-reported adherence1 to lipid-lowering therapies, stratified by diabetes and ASCVD status.
See this image and copyright information in PMC

References

    1. Wu Y, Benjamin EJ, MacMahon S. Prevention and control of cardiovascular disease in the rapidly changing economy of China. Circulation. 2016;133(24):2545–2560. - PMC - PubMed
    1. United Nations Department of Economic and Social Affairs Population Division. World population ageing. Ney York (NY): United Nations; 2013. (World population ageing series).
    1. Chen WW, Gao RL, Liu LS, et al. China cardiovascular diseases report 2015: a summary. J Geriatr Cardiol. 2017;14(1):1–10. - PMC - PubMed
    1. Verges B. Pathophysiology of diabetic dyslipidaemia: where are we? Diabetologia. 2015;58(5):886–899. - PMC - PubMed
    1. Anderson P, Benford M, Harris N, et al. Real-world physician and patient behaviour across countries: Disease-Specific Programmes – a means to understand. Curr Med Res Opin. 2008;24(11):3063–3072. - PubMed

LinkOut - more resources