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Case Reports
. 2017 Aug;32(3):291-294.
doi: 10.4266/kjccm.2016.00052. Epub 2016 Dec 29.

Clozapine Induced Neuroleptic Malignant Syndrome

Yong Suk Jo  1 , Hyung Ah Jo  2 , Byung Chul Yu  2 , Jung Hoon Shin  3 , Kook-Hwan Oh  2
Affiliations
Case Reports

Clozapine Induced Neuroleptic Malignant Syndrome

Yong Suk Jo et al. Korean J Crit Care Med. 2017 Aug.

Abstract

Neuroleptic malignant syndrome is a rare, but potentially life-threatening adverse event associated with the use of neuroleptic agents. We describe the case of a 47-year-old schizophrenic woman who was treated with clozapine for years. The patient developed acute renal failure with pulmonary edema, and underwent mechanical ventilation and hemodialysis.

Keywords: acute kidney injury; clozapine; neuroleptic malignant syndrome; rhabdomyolysis.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1.
Fig. 1.
A chest radiograph reveals prominent bilateral vascular markings suggestive of acute pulmonary edema.
Fig. 2.
Fig. 2.
A chest radiograph reveals improved bilateral pulmonary edema compared with a chest radiograph taken 3 days prior.
See this image and copyright information in PMC

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