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Review
. 2017 Jun 28:8:26-32.
doi: 10.1016/j.jctube.2017.06.002. eCollection 2017 Aug.

Fifteen-year clinical experience with Mycobacterium haemophilum at the Mayo Clinic: A case series

Harmony L Tyner  1 , John W Wilson  2
Affiliations
Review

Fifteen-year clinical experience with Mycobacterium haemophilum at the Mayo Clinic: A case series

Harmony L Tyner et al. J Clin Tuberc Other Mycobact Dis. .

Abstract

Mycobacterium haemophilum is an uncommonly encountered acid-fast staining bacillus (AFB) that can cause a broad range of infections. We describe a tertiary care center's experience with M. haemophilum infections identified from 2000 to 2015. Ten adult patients were identified with M. haemophilum infections, and most had immunocompromising conditions. M. haemophilum presented in one of two syndromes: a peripheral cutaneous infection presenting with skin nodularity and local invasion, and a cervicofacial infection involving regional lymph nodes. Duration of therapy was variable (0-18 months) and was dependent on the underlying syndrome and immunological status of the patient. Treatment responses were favorable in all patients. During therapy, three patients developed culture-negative aseptic cutaneous lesions, consistent with immunologic reconstitution inflammatory syndrome (IRIS); we postulate that such reactions may not be uncommon with select M. haemophilum infections.

Keywords: Acid fast bacilli; Case series; Mycobacterium haemophilum.

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Figures

Fig 1
Fig. 1
M. haemophilum clinical presentations.
See this image and copyright information in PMC

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