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Editorial
. 2018 Nov 29;2(6):e154.
doi: 10.1097/HS9.0000000000000154. eCollection 2018 Dec.

FXII: The Cuckoo in the Nest

Roger E G Schutgens  1
Affiliations
Editorial

FXII: The Cuckoo in the Nest

Roger E G Schutgens. Hemasphere. .
No abstract available

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Conflict of interest statement

The authors have indicated they have no potential conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Thromboinflammatory activities of FXII in vivo (from Maas and Renné).
Figure 2
Figure 2
Role of FXII in inflammation and wound healing (from Stavrou et al).
See this image and copyright information in PMC

References

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    1. Davie EW, Ratnoff OD. Waterfall sequence for intrinsic blood clotting. Science. 1964;145:1310–1312. - PubMed
    1. Maas C, Renné T. Coagulation factor XII in thrombosis and inflammation. Blood. 2018;131:1903–1909. - PubMed
    1. De Maat S, Hofman ZLM, Maas C. Hereditary angioedema: the plasma contact system out of control. J Thromb Haemost. 2018;16:1674–1685. - PubMed
    1. Cao H, Biondo M, Lioe H, et al. Antibody-mediated inhibition of FXIIa blocks downstream bradykinin generation. J Allergy Clin Immunol. 2018;142:1355–1358. - PubMed

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