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Review

Advanced Multiparametric Imaging for Response Assessment to Tumor-Treating Fields in Patients with Glioblastoma

Suyash Mohan  1 , Sumei Wang  1 , Sanjeev Chawla  1
Sergey Makarov  1 , Marc Horner  2 , Gregory Noetscher  3
, editors.
In: Brain and Human Body Modeling: Computational Human Modeling at EMBC 2018 [Internet]. Cham (CH): Springer; 2019. Chapter 9.
.
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Review

Advanced Multiparametric Imaging for Response Assessment to Tumor-Treating Fields in Patients with Glioblastoma

Suyash Mohan et al.
Free Books & Documents

Excerpt

Glioblastoma (GBM) is the most common malignant brain tumor and accounts for 70% of all primary brain tumors in adults. Despite aggressive multimodal therapy including surgery, radiation, and chemotherapy, the prognosis remains poor with a median survival of around 2 years. Tumor-treating fields (TTFields) is a new frontier in cancer therapy and has been recently approved for the treatment of GBM. This chapter discusses emerging concepts of brain tumor management, with special emphasis toward novel therapeutic approaches. Recent neuroimaging advances including novel physiologic and metabolic neuroimaging techniques and their role in monitoring treatment-related temporal characteristics and assessing response to this unique treatment modality will also be reviewed.

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