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Review
. 2021 Mar 1;43(2):e203-e206.
doi: 10.1097/MPH.0000000000001674.

Pediatric Metastatic Cardiac Angiosarcoma Successfully Treated With Multimodal Therapy: Case Report and Review of Literature

Jane Koo  1 , Jessica Knight-Perry  1 , Csaba Galambos  2 , Lorna P Browne  3 , Carrye R Cost  1
Affiliations
Review

Pediatric Metastatic Cardiac Angiosarcoma Successfully Treated With Multimodal Therapy: Case Report and Review of Literature

Jane Koo et al. J Pediatr Hematol Oncol. .

Abstract

Cardiac angiosarcoma (AS) is an extremely rare, malignant vascular tumor with <10 cases reported in the pediatric literature. Prognosis is dismal with overall survival often <1 year from initial diagnosis. In this report, we present the case of a 10-year-old boy with metastatic cardiac AS who is currently alive and is the longest pediatric survivor of metastatic cardiac AS reported in the literature. This is the only published pediatric case to successfully use a combination of surgical resection, conventional chemotherapy, radiation and targeted therapies including bevacizumab and pazopanib for metastatic cardiac AS.

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Conflict of interest statement

The authors declare no conflict of interest.

References

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