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Review
. 2020 Feb 1;126(3):477-486.
doi: 10.1002/cncr.32619. Epub 2019 Nov 14.

Neurologic complications of melanoma

Justine V Cohen  1 , Nancy Wang  2 , Vyshak A Venur  2 , Matthew J Hadfield  3 , Daniel P Cahill  4 , Kevin Oh  5 , Priscilla K Brastianos  1
Affiliations
Free article
Review

Neurologic complications of melanoma

Justine V Cohen et al. Cancer. .
Free article

Abstract

Neurologic complications are common in patients with melanoma and are often associated with a poor prognosis. In an era with new, effective treatments, patients are living longer, and this has resulted in an increase in complications of both the disease and the therapy. A multidisciplinary approach to neurologic complications in patients with melanoma, with involvement from medical oncology, neuro-oncology, radiation oncology, and often neurosurgery, is necessary. In this review, neurologic complications of melanoma, including clinical implications and treatment strategies, are described.

Keywords: melanoma; neuro-oncology; neurologic.

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References

    1. Chang PC, Fischbein NJ, McCalmont TH, et al. Perineural spread of malignant melanoma of the head and neck: clinical and imaging features. AJNR Am J Neuroradiol. 2004;25:5-11.
    1. Lee TJ, Glastonbury CM, Buckley AF, Eisele DW, Hawkins RA. Perineural spread of melanoma demonstrated by F-18 FDG PET with MRI and pathologic correlation. Clin Nucl Med. 2008;33:106-108.
    1. Barnett SL, Wells MJ, Mickey B, Hatanpaa KJ. Perineural extension of cutaneous desmoplastic melanoma mimicking an intracranial malignant peripheral nerve sheath tumor. Case report. J Neurosurg. 2011;115:273-277.
    1. Balink H, de Visscher JG, van der Meij EH. Recurrent head and neck desmoplastic melanoma with perineural spread along the nervus mandibularis revealed by 18F-FDG PET/CT. Int J Oral Maxillofac Surg. 2014;43:941-943.
    1. Namikawa K, Aung PP, Gershenwald JE, Milton DR, Prieto VG. Clinical impact of ulceration width, lymphovascular invasion, microscopic satellitosis, perineural invasion, and mitotic rate in patients undergoing sentinel lymph node biopsy for cutaneous melanoma: a retrospective observational study at a comprehensive cancer center. Cancer Med. 2018;7:583-593.

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