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Comment
. 2019 Nov 13;26(5):567-568.
doi: 10.1016/j.chom.2019.10.017.

Cyclic Nucleotide Signaling: A Second Messenger of Death

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Cyclic Nucleotide Signaling: A Second Messenger of Death

Nina Molin Høyland-Kroghsbo. Cell Host Microbe. .
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Abstract

All life forms rely on defenses to fight off viruses that prey on them. Intriguingly, bacteria often develop the blueprints for these. Recently published in Nature, Cohen et al. (2019) uncover a widespread bacterial anti-viral defense system, which may be the evolutionary precursor to the metazoan cGAS-STING immune pathway.

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