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. 2019 Nov 14;19(1):834.
doi: 10.1186/s12913-019-4613-0.

Economic evaluation studies in the field of HIV/AIDS: bibliometric analysis on research development and scopes (GAPRESEARCH)

Bach Xuan Tran  1   2 , Long Hoang Nguyen  3 , Hugo C Turner  4 , Son Nghiem  5 , Giang Thu Vu  6 , Cuong Tat Nguyen  7 , Carl A Latkin  8 , Cyrus S H Ho  9 , Roger C M Ho  3   10   11
Affiliations

Economic evaluation studies in the field of HIV/AIDS: bibliometric analysis on research development and scopes (GAPRESEARCH)

Bach Xuan Tran et al. BMC Health Serv Res. .

Abstract

Background: The rapid decrease in international funding for HIV/AIDS has been challenging for many nations to effectively mobilize and allocate their limited resources for HIV/AIDS programs. Economic evaluations can help inform decisions and strategic planning. This study aims to examine the trends and patterns in economic evaluation studies in the field of HIV/AIDS and determine their research landscapes.

Methods: Using the Web of Science databases, we synthesized the number of papers and citations on HIV/AIDS and economic evaluation from 1990 to 2017. Collaborations between authors and countries, networks of keywords and research topics were visualized using frequency of co-occurrence and Jaccards' similarity index. A Latent Dirichlet Allocation (LDA) analysis to categorize papers into different topics/themes.

Results: A total of 372 economic evaluation papers were selected, including 351 cost-effectiveness analyses (CEA), 11 cost-utility analyses (CUA), 12 cost-benefit analyses (CBA). The growth of publications, their citations and usages have increased remarkably over the years. Major research topics in economic evaluation studies consisted of antiretroviral therapy (ART) initiation and treatment; drug use prevention interventions and prevention of mother-to-child transmission interventions. Moreover, lack of contextualized evidence was found in specific settings with high burden HIV epidemics, as well as emerging most-at-risk populations such as trans-genders or migrants.

Conclusion: This study highlights the knowledge and geographical discrepancies in HIV/AIDS economic evaluation literature. Future research directions are also informed for advancing economic evaluation in HIV/AIDS research.

Keywords: Bibliometric; Content analysis; Economic evaluation; HIV/AIDS; Health economics.

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Conflict of interest statement

The authors declare that they have no competing interests. Bach Tran is a member of the editorial board of BMC Health Services Research. HCT is supported by the Wellcome Trust [089276/B/09/7].

Figures

Fig. 1
Fig. 1
Selection of papers
Fig. 2
Fig. 2
Collaboration network between the top 20 countries by the number of publications. The outer rim reflects the volume of collaborations between one country with other countries in the top 20, showing collaboration among countries. Abbreviation: USA, the United States of America; ENG, England; GER, Germany; AUS, Australia; NET, Netherlands; CAN, Canada; SAF, South Africa; FRA, France; SWI, Switzerland; UGA, Uganda; SPA, Spain; MEX, Mexico; IND, India; ZAM, Zambia, KEN, Kenya, TAN, Tanzania; BEL, Belgium; SWE, Sweden; BRA, Brazil; VIE, Vietnam
Fig. 3
Fig. 3
Co-occurrence of most frequent author’s keywords. Note: the colors refer to different clusters; the nodes size reflects keywords’ occurrences; lines’ thickness was visualized according to the strength of the relationship between two keywords
Fig. 4
Fig. 4
Changes in research topics development
Fig. 5
Fig. 5
Proximity Plot of “cost-effectiveness analysis” (CEA), “cost-utility analysis” (CUA), “cost-benefit analysis” (CBA) terms with top 50 most frequent concurrence terms in 372 Economic Evaluation Studies’ abstracts. The x-axis shows the Jaccard coefficient which reflect similarities amning certain sample sets. It refers to the range of the intersection divided by the range of the union of the sample sets
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