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Editorial
. 2019 Dec;198(3):292-293.
doi: 10.1111/cei.13396.

Historical and new insights into pathogenesis of type 1 diabetes

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Editorial

Historical and new insights into pathogenesis of type 1 diabetes

F S Wong et al. Clin Exp Immunol. 2019 Dec.

Abstract

In recent years, there have been exciting new insights into pathogenesis of type 1 diabetes in a number of areas of immunology. In this edition, a collection of four review articles are presented, which encompass new findings presented at the Immunology of Diabetes Society meeting in London 2018. The articles are focused particularly in 4 related areas of investigation, which include autoantibodies in type 1 diabetes, new autoantigenic targets for CD4 T cells, trafficking of immune cells to the pancreas and islet-immune interactions in the pancreas.

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References

    1. Bonifacio E, Achenbach P. Birth and coming of age of islet autoantibodies. Clin Exp Immunol 2019; 198:294–305. - PMC - PubMed
    1. Wiles TA, Delong T. HIPs and HIP‐reactive T cells. Clin Exp Immunol 2019; 198:306–13. - PMC - PubMed
    1. Sandor AM, Jacobelli J, Friedman RS. Immune cell trafficking to the islets during type 1 diabetes. Clin Exp Immunol 2019; 198:314–25. - PMC - PubMed
    1. Peters L, Posgai A, Brusko TM. Islet–immune interactions in type 1 diabetes: the nexus of beta cell destruction. Clin Exp Immunol 2019; 198:326–40. - PMC - PubMed

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