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. 2019 Sep;54(3):236-240.
doi: 10.5045/br.2019.54.3.236. Epub 2019 Sep 25.

Successful treatment of non-IgM lymphoplasmacytic lymphoma by bortezomib-containing regimen: case reports and review of literature

Kenichi Ito  1 , Risa Nishiyama  1 , Kazuhiko Hirano  2 , Kazuaki Yamada  2 , Naohiro Sekiguchi  1   3
Affiliations

Successful treatment of non-IgM lymphoplasmacytic lymphoma by bortezomib-containing regimen: case reports and review of literature

Kenichi Ito et al. Blood Res. 2019 Sep.
No abstract available

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Conflict of interest statement

Authors' Disclosures of Potential Conflicts of Interest: No potential conflicts of interest relevant to this article were reported.

Figures

Fig. 1
Fig. 1. Computed tomography at diagnosis. (A) A soft tissue mass in the mesenteric lymph nodes in Case 1. (B) A bulky mass in the mediastinum in Case 2.
Fig. 2
Fig. 2. (A–C) Neoplastic cells in the bone marrow in Case 1. (A) Hematoxylin and eosin staining: diffused invasion of the neoplastic cells was observed in the bone marrow biopsy specimen (original magnification ×400). (B) Staining with CD138: The cytoplasm of the neoplastic lymphoplasmacytes and plasmacytes was strongly positive for CD138 (×400). (C) Staining with CD20: The cytoplasm of the neoplastic small lymphocytes and lymphoplasmacytic cells were strongly positive for CD20 (×630). (D–F) The neoplastic cells of the mediastinum tumor mass in Case 2. (D) Hematoxylin and eosin staining: Neoplastic lymphocytes, lymphoplasmacytes, and plasmacytes were noted in the mediastinum tumor specimen (×400). (E) Staining with CD20: The cytoplasm of the neoplastic lymphocytes was strongly positive for CD20 (×400). (F) Staining with CD138: The cytoplasm of the neoplastic lymphoplasmacytes and plasmacytes was strongly positive for CD138 (×400).
See this image and copyright information in PMC

References

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