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Review
. 2019 Nov;48(11 Pt 1):1244-1248.
doi: 10.1016/j.lpm.2019.10.008. Epub 2019 Nov 12.

[Endogenous and exogenous estrogens]

[Article in French]
Affiliations
Review

[Endogenous and exogenous estrogens]

[Article in French]
Theodora Bejan-Angoulvant et al. Presse Med. 2019 Nov.

Abstract

Before menopause, women are protected from the risk of hypertension and atherosclerosis by endogenous estrogens. Estrogens have a vasoprotective role, while progesterone seems to have a neutral effect. Exogenous estrogens used in menopausal treatment have vascular effects. These effects depend of type, dose and administration type, and with age and atherosclerosis stages. Synthetic progestins have varying clinical effects. Each drug must be evaluated separately.

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