The Impact of Obesity in Heart Failure

Salvatore Carbone¹, Carl J Lavie², Andrew Elagizi², Ross Arena³, Hector O Ventura⁴

Affiliations

¹ Department of Kinesiology & Health Sciences, College of Humanities & Sciences, Virginia Commonwealth University, 1020 W Grace St, 500 Academic Centre, Room 113c, Richmond, VA 23220, USA; Department of Internal Medicine, Division of Cardiology, VCU Pauley Heart Center, Virginia Commonwealth University, 1200 E Broad St, Richmond, VA 23219, USA. Electronic address: scarbone@vcu.edu.
² John Ochsner Heart and Vascular Institute, Ochsner Clinical School-The University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, LA 70121-2483, USA.
³ Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL 60612, USA; TotalCardiology Research Network, Calgary, Alberta, Canada.
⁴ Cardiomyopathy and Heart Transplantation, Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School, University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, LA 70121-2483, USA.

PMID: 31735317
DOI: 10.1016/j.hfc.2019.08.008

Review

The Impact of Obesity in Heart Failure

Salvatore Carbone et al. Heart Fail Clin. 2020 Jan.

. 2020 Jan;16(1):71-80.

doi: 10.1016/j.hfc.2019.08.008.

Authors

Salvatore Carbone¹, Carl J Lavie², Andrew Elagizi², Ross Arena³, Hector O Ventura⁴

Affiliations

¹ Department of Kinesiology & Health Sciences, College of Humanities & Sciences, Virginia Commonwealth University, 1020 W Grace St, 500 Academic Centre, Room 113c, Richmond, VA 23220, USA; Department of Internal Medicine, Division of Cardiology, VCU Pauley Heart Center, Virginia Commonwealth University, 1200 E Broad St, Richmond, VA 23219, USA. Electronic address: scarbone@vcu.edu.
² John Ochsner Heart and Vascular Institute, Ochsner Clinical School-The University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, LA 70121-2483, USA.
³ Department of Physical Therapy, College of Applied Health Sciences, University of Illinois at Chicago, 1919 W Taylor Street, Chicago, IL 60612, USA; TotalCardiology Research Network, Calgary, Alberta, Canada.
⁴ Cardiomyopathy and Heart Transplantation, Department of Cardiovascular Diseases, John Ochsner Heart and Vascular Institute, Ochsner Clinical School, University of Queensland School of Medicine, 1514 Jefferson Highway, New Orleans, LA 70121-2483, USA.

PMID: 31735317
DOI: 10.1016/j.hfc.2019.08.008

Abstract

Obesity has reached worldwide epidemic proportions, adversely impacting health on a global scale. Overweight and obesity adversely impact cardiac structure and function, affecting systolic and diastolic ventricular function. Studies and meta-analyses have documented an obesity paradox in large heart failure cohorts, where overweight and obese individuals with established heart failure have a better short- and medium-term prognosis compared with lean patients; this relationship is strongly impacted by level of cardiorespiratory fitness. There are implications for therapies aimed at increasing lean and muscle mass, and weight loss, for the prevention and treatment of compared with in patients with concomitant obesity.

Keywords: Body composition; Cardiorespiratory fitness; Heart failure; Obesity; Obesity paradox.

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The Impact of Obesity in Heart Failure

Affiliations

The Impact of Obesity in Heart Failure

Authors

Affiliations

Abstract

Publication types

MeSH terms

LinkOut - more resources

Full Text Sources

Medical